{"id":4567,"date":"2020-07-29T10:20:32","date_gmt":"2020-07-29T02:20:32","guid":{"rendered":"http:\/\/clbiomed.cn\/?post_type=portfolio&p=4567"},"modified":"2020-08-03T11:31:58","modified_gmt":"2020-08-03T03:31:58","slug":"turning-point-therapeutics","status":"publish","type":"portfolio","link":"https:\/\/clbiomed.com\/projects\/turning-point-therapeutics\/","title":{"rendered":"Turning Point Therapeutics"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-kcpjs20w-1d234c774d0840ba9e0b2f6776ad0d7f\">\n.avia-section.av-kcpjs20w-1d234c774d0840ba9e0b2f6776ad0d7f{\nmargin-top:-45px;\nmargin-bottom:0px;\n}\n#top .avia-section.av-kcpjs20w-1d234c774d0840ba9e0b2f6776ad0d7f .scroll-down-link{\ncolor:#e8865e;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-kcpjs20w-1d234c774d0840ba9e0b2f6776ad0d7f main_color avia-section-default avia-shadow  avia-builder-el-0  el_before_av_section  avia-builder-el-first  avia-bg-style-scroll 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itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-3775 avia-img-lazy-loading-not-3775 avia_image ' src=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment.jpg\" alt='' title='healthcare-investment'  height=\"418\" width=\"1600\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment.jpg 1600w, https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment-300x78.jpg 300w, https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment-1030x269.jpg 1030w, https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment-768x201.jpg 768w, https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment-1536x401.jpg 1536w, https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment-1500x392.jpg 1500w, https:\/\/clbiomed.com\/wp-content\/uploads\/2011\/12\/healthcare-investment-705x184.jpg 705w\" sizes=\"(max-width: 1600px) 100vw, 1600px\" \/><\/div><\/div><\/div><\/div><div class='flex_column av-8gpjx-1ac0d8c22a2e7a40d65c61235765a2db av_one_third  avia-builder-el-3  el_after_av_one_full  el_before_av_two_third  first flex_column_div column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4asl3b-4577942e7537d8ca516c6c55a95eb3bd\">\n#top .av-special-heading.av-4asl3b-4577942e7537d8ca516c6c55a95eb3bd{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-4asl3b-4577942e7537d8ca516c6c55a95eb3bd .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-4asl3b-4577942e7537d8ca516c6c55a95eb3bd .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-4asl3b-4577942e7537d8ca516c6c55a95eb3bd av-special-heading-h3  avia-builder-el-4  el_before_av_textblock  avia-builder-el-first '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >Turning Point Therapeutics<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-q1u9-9170247beb4a46353c780d481d7f8740'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>2013\u5e74\u6210\u7acb\u4e8e\u7f8e\u56fd\u5723\u5730\u4e9a\u54e5\uff0c2019\u5e744\u6708\u5728\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02 (<a href=\"https:\/\/finance.yahoo.com\/quote\/TPTX\">NASDAQ : TPTX<\/a>)\u3002\u81f4\u529b\u4e8e\u5f00\u53d1\u6cbb\u7597\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u7684\u7cbe\u51c6\u836f\u7269\u3002<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-4577 size-medium\" src=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-300x63.png\" alt=\"\" width=\"200\" srcset=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-300x63.png 300w, https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint.png 452w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<div  class='hr av-6mlb1-74e9675ae1a59c1611b5feadb82e91ff hr-short  avia-builder-el-6  avia-builder-el-no-sibling  hr-left'><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<ul>\n<li>\u9879\u76ee\u540d: Turning Point Therapeutics<\/li>\n<li>\u9886\u57df: \u514d\u75ab\u6cbb\u7597<\/li>\n<li>\u7f51\u7ad9: <a href=\"https:\/\/tptherapeutics.com\">www.tptherapeutics.com<\/a><\/li>\n<li>\u5b9e\u65f6\u80a1\u7968\u884c\u60c5\uff1a<span class=\"stock_quote sqitem  zero\" title=\"TPTX (Last trade 2022-09-08 US\/Eastern)\">TPTX 76.01 0.00 0.00%<\/span><\/li>\n<\/ul>\n<\/div><\/section><\/p><\/div><div class='flex_column av-6cqd9-822b33d70423b5389e1ea85bbe8988a4 av_two_third  avia-builder-el-7  el_after_av_one_third  avia-builder-el-last  flex_column_div column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2ft3tj-85363728948e32511d693bfe4ad88a32\">\n#top .av-special-heading.av-2ft3tj-85363728948e32511d693bfe4ad88a32{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-2ft3tj-85363728948e32511d693bfe4ad88a32 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-2ft3tj-85363728948e32511d693bfe4ad88a32 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-2ft3tj-85363728948e32511d693bfe4ad88a32 av-special-heading-h3  avia-builder-el-8  el_before_av_tab_container  avia-builder-el-first '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >\u9879\u76ee\u8be6\u60c5<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<div  class='tabcontainer av-4yqwp-359e32db58ff3a7acc1f97d99051ccdd top_tab  avia-builder-el-9  el_after_av_heading  avia-builder-el-last ' role='tablist'>\n<section class='av_tab_section av_tab_section av-gvit3-42fc578b8437bf20dca21375d0169580'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='tab active_tab' role='tab' tabindex='0' data-fake-id='#tab-id-1' aria-controls='tab-id-1-content'  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue844' data-av_iconfont='entypo-fontello'><\/span>\u7b80\u4ecb<\/div><div id='tab-id-1-content' class='tab_content active_tab_content' aria-hidden=\"false\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><p>\u4f4d\u4e8e\u52a0\u5dde\u7684\u4e34\u5e8a\u9636\u6bb5\u836f\u7269\u8bbe\u8ba1\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u6cbb\u7597\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u7684\u7cbe\u51c6\u836f\u7269\u3002\u4e3a\u5177\u6709\u4e8c\u7ea7\u6297\u6027\u7a81\u53d8\uff0c\u65b0\u53d1\u73b0\u7684\u75be\u75c5\u9a71\u52a8\u9776\u6807\u4ee5\u53ca\u8c03\u8282\u80bf\u7624\u5fae\u73af\u5883\u548c\u80bf\u7624\u514d\u75ab\u7684\u6f5c\u5728\u9776\u6807\u7684\u5df2\u5efa\u7acb\u764c\u57fa\u56e0\u9a71\u52a8\u56e0\u5b50\u8bbe\u8ba1\u65b0\u7684\u5316\u5b66\u4ea7\u54c1\u3002\u4ea7\u54c1\u7ba1\u7ebf\u62e5\u6709\u591a\u4e2a\u5355\u72ec\u6cbb\u7597\u548c\u8054\u5408\u6cbb\u7597\u4ea7\u54c1\u3002\u8fd1\u671f\u548c\u518d\u9f0e\u836f\u4e1a\u8fbe\u6210\u4e2d\u56fd\u533a\u5408\u4f5c\u3002\u4e3b\u8981\u6295\u8d44\u4eba\uff1aLilly Asia Ventures, HBM Healthcare Investments AG, Foresite Capital, Kenson Ventures, OrbiMed, SR One, Cormorant Asset Management\u3002<\/p>\n<h4>\u6280\u672f\u5e73\u53f0<\/h4>\n<p><a href=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech.jpg\"><img decoding=\"async\" class=\"aligncenter wp-image-4575 size-full\" src=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech.jpg\" alt=\"\" width=\"1430\" height=\"634\" srcset=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech.jpg 1430w, https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech-300x133.jpg 300w, https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech-1030x457.jpg 1030w, https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech-768x340.jpg 768w, https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-tech-705x313.jpg 705w\" sizes=\"(max-width: 1430px) 100vw, 1430px\" \/><\/a><\/p>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-3kaso7-c4f73af226c7b3899094353a2338ab1e'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='tab' role='tab' tabindex='0' data-fake-id='#tab-id-2' aria-controls='tab-id-2-content'  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello'><\/span>\u56e2\u961f<\/div><div id='tab-id-2-content' class='tab_content' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Athena M. Countouriotis, M.D. &#8212; President, Chief Executive Officer\uff0c\u9996\u5e2d\u6267\u884c\u5b98Countouriotis\u535a\u58eb\u62e5\u6709\u5e7f\u6cdb\u7684\u80bf\u7624\u5b66\u751f\u7269\u6280\u672f\u9886\u5bfc\u7ecf\u9a8c\uff0c\u6307\u5bfc\u591a\u4e2a\u5f00\u53d1\u8ba1\u5212\u83b7\u5f97\u6279\u51c6\u3002\u5979\u7684\u7ecf\u9a8c\u5305\u62ec\u5728\u8840\u6db2\u5b66\u548c\u5b9e\u4f53\u7624\u9002\u5e94\u75c7\u4e2d\u4f7f\u7528\u5927\u5206\u5b50\u548c\u5c0f\u5206\u5b50\u7597\u6cd5\uff0c\u5e76\u5728\u7f8e\u56fd\u548c\u6b27\u6d32\u83b7\u5f97\u4e86\u591a\u4e2a\u76d1\u7ba1\u90e8\u95e8\u7684\u6279\u51c6\u3002\u5979\u4e8e2018\u5e745\u6708\u52a0\u5165\u516c\u53f8\uff0c\u62c5\u4efb\u6267\u884c\u526f\u603b\u88c1\u517c\u9996\u5e2d\u533b\u5b66\u5b98\uff0c\u4ee5\u4fc3\u8fdbrepotrectinib\u7684\u4e34\u5e8a\u5f00\u53d1\u3002\u5979\u4e4b\u524d\u66fe\u62c5\u4efbAdverum Biotechnologies\u7684\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u9996\u5e2d\u533b\u5b66\u5b98\uff0c\u5728\u6b64\u4e4b\u524d\uff0c\u4ed6\u66fe\u62c5\u4efbHalozyme Therapeutics\u7684\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u9996\u5e2d\u533b\u5b66\u5b98\u3002 Countouriotis\u535a\u58eb\u8fd8\u66fe\u62c5\u4efbAmbit Biosciences\u7684\u9996\u5e2d\u533b\u5b66\u5b98\uff0c\u5728\u90a3\u91cc\u5979\u5e2e\u52a9\u9886\u5bfc\u4e86\u8be5\u516c\u53f8\u7684\u9996\u6b21\u516c\u5f00\u52df\u80a1\uff0c\u5e76\u8d1f\u8d23quizartinib\u7684\u4e34\u5e8a\u5f00\u53d1\uff0c\u76f4\u5230\u8be5\u836f\u4e8e2014\u5e7411\u6708\u88abDaiichi Sankyo\u6536\u8d2d\u4e3a\u6b62\u3002\u5728\u5979\u804c\u4e1a\u751f\u6daf\u7684\u65e9\u671f\uff0cCountouriotis\u535a\u58eb\u9886\u5bfc\u8f89\u745e\u516c\u53f8\u548c\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u516c\u53f8\u5185\u90e8\u7684\u5404\u79cd\u4e34\u5e8a\u5f00\u53d1\u7ec4\u7ec7\u7528\u4e8e\u80bf\u7624\u6cbb\u7597\uff0c\u5305\u62ecSutent\u00ae\uff0cMylotarg\u2122\uff0cBosulif\u00ae\u548cSprycel\u00ae\u3002Countouriotis\u535a\u58eb\u8fd8\u62c5\u4efbIovance Biotherapeutics\u548cPassage Bio\u7684\u8463\u4e8b\u4f1a\u6210\u5458\u3002\u62e5\u6709\u5854\u592b\u8328\u5927\u5b66\u533b\u5b66\u9662\u7684\u533b\u5b66\u535a\u58eb\u5b66\u4f4d\u3002\u5979\u5728\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u63a5\u53d7\u4e86\u513f\u79d1\u7684\u521d\u59cb\u533b\u5b66\u57f9\u8bad\uff0c\u5e76\u5728\u513f\u79d1\u8840\u6db2\u5b66\/\u80bf\u7624\u5b66\u8ba1\u5212\u7684\u5f17\u96f7\u5fb7\u00b7\u54c8\u94a6\u68ee\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u63a5\u53d7\u4e86\u5176\u4ed6\u57f9\u8bad\u3002<\/li>\n<li>Mohammad Hirmand, M.D. &#8212; Executive Vice President and Chief Medical Officer\uff0c\u6267\u884c\u526f\u603b\u88c1\u517c\u9996\u5e2d\u533b\u5b66\u5b98\uff0c\u8d1f\u8d23\u4e34\u5e8a\u5f00\u53d1\uff0c\u4e34\u5e8a\u8fd0\u8425\u548c\u76d1\u7ba1\u4e8b\u52a1\u3002 Hirmand\u535a\u58eb\u62e5\u670920\u591a\u5e74\u7684\u751f\u7269\u6280\u672f\u4e34\u5e8a\u5f00\u53d1\u7ecf\u9a8c\uff0c\u66fe\u662fPeloton Therapeutics\u7684\u9996\u5e2d\u8425\u9500\u5b98\uff0c\u8be5\u516c\u53f8\u4e8e2019\u5e747\u6708\u88ab\u9ed8\u514b\u6536\u8d2d\u3002\u57282017\u5e74\u52a0\u5165Peloton\u4e4b\u524d\uff0cHirmand\u535a\u58eb\u66fe\u88ab\u8f89\u745e\u516c\u53f8\u6536\u8d2d\uff0c\u62c5\u4efbMedivation\u7684\u9996\u5e2d\u8425\u9500\u5b98\u3002\u4ed6\u901a\u8fc7\u4e34\u5e8a\u8bd5\u9a8c\u5728\u4fc3\u8fdbXTANDI\u00ae\uff08enzalutamide\uff09\u65b9\u9762\u8d77\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u8be5\u8bd5\u9a8c\u5bfc\u81f4\u5176\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\u7684\u6279\u51c6\uff0c\u53ef\u7528\u4e8e\u6cbb\u7597\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c\u3002\u4ed6\u7684\u804c\u8d23\u8fd8\u5305\u62ec\u805aADP\u6838\u7cd6\u805a\u5408\u9176\uff08PARP\uff09\u6291\u5236\u5242talazoparib\u7684\u8bb8\u53ef\u53ca\u5168\u7403\u4e34\u5e8a\u5f00\u53d1\u3002Hirmand\u5eb7\u5948\u5c14\u5927\u5b66\u751f\u7269\u79d1\u5b66\u4e0e\u7ecf\u6d4e\u5b66\u535a\u58eb\u5b66\u4f4d\u3002<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-7odif-05c098a8105e478587d79305ae51c8fb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='tab' role='tab' tabindex='0' data-fake-id='#tab-id-3' aria-controls='tab-id-3-content'  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue811' data-av_iconfont='entypo-fontello'><\/span>\u4ea7\u54c1\u7ba1\u7ebf<\/div><div id='tab-id-3-content' class='tab_content' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><p><a href=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-pipeline.jpg\"><img decoding=\"async\" class=\"aligncenter wp-image-4573 size-full\" src=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-pipeline.jpg\" alt=\"\" width=\"1127\" height=\"708\" srcset=\"https:\/\/clbiomed.com\/wp-content\/uploads\/2020\/07\/TurningPoint-pipeline.jpg 1127w, 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