{"id":6087,"date":"2020-09-10T15:27:29","date_gmt":"2020-09-10T07:27:29","guid":{"rendered":"http:\/\/clbiomed.cn\/?p=6087"},"modified":"2020-09-10T18:18:06","modified_gmt":"2020-09-10T10:18:06","slug":"https-mp-weixin-qq-com-s__bizmzi2ntqynjmxoqmid2247488837idx1sn4346706ba3d8475bb77112962bf5bc5dchksmea9cd1a5ddeb58b3a5d23253ad55cdb70cd8207664e6b7ccf28b7f036f80af5ba81d0d04984etoken1958","status":"publish","type":"post","link":"https:\/\/clbiomed.com\/2020\/09\/https-mp-weixin-qq-com-s__bizmzi2ntqynjmxoqmid2247488837idx1sn4346706ba3d8475bb77112962bf5bc5dchksmea9cd1a5ddeb58b3a5d23253ad55cdb70cd8207664e6b7ccf28b7f036f80af5ba81d0d04984etoken1958\/","title":{"rendered":"\u521b\u65b0\u6539\u53d8\u4e16\u754c | 2020\u4e2d\u56fd\u521b\u65b0\u836f\u7814\u53d1\u524d\u6cbf\u8bba\u575b\u7cbe\u5f69\u56de\u987e"},"content":{"rendered":"

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 <\/p>\n

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 <\/p>\n

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\u5609\u5174\u4f18\u535a\u7684\u7ec6\u80de\u9776\u5411\u6027\u9176\u964d\u89e3\u836f\u7269TED\u5e73\u53f0\u6709\u522b\u4e8e\u4f20\u7edfPROTAC\uff0c\u5177\u6709\u53cc\u91cd\u9776\u5411\u3001\u6709\u6548\u4f20\u9012\u3001\u591a\u529f\u80fd\u5316\u3001\u66f4\u52a0\u5b89\u5168\u7b49\u7279\u70b9\uff0c\u540c\u65f6\u7814\u53d1\u7ba1\u7ebf\u8bbe\u7f6e\u4e5f\u5341\u5206\u6ce8\u91cd\u4e34\u5e8a\u9700\u6c42\uff0c\u76ee\u524d\u5728\u7814\u7684\u91cd\u70b9\u9879\u76ee\u4e2d\uff0c\u4e00\u79cd\u5206\u5b50\u53ef\u540c\u65f6\u964d\u89e3\u4e24\u79cd\u81f4\u764c\u86cb\u767d\uff0c\u5e76\u5df2\u5728\u52a8\u7269\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u4e86\u826f\u597d\u7684\u836f\u6548\u3002<\/p>\n

\"\"<\/p>\n

 <\/p>\n

\u300a\u5728\u4e2d\u56fd\u5f00\u521bfirst-in-class\u521b\u65b0\u836f\u4e4b\u8def\u7684\u63a2\u7d22\u300b<\/strong><\/span><\/p>\n

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\"\"<\/p>\n

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\u672a\u6765\uff0c\u7ef4\u6cf0\u745e\u9686\u5c06\u7ee7\u7eed\u9488\u5bf9\u5404\u79cd\u7ec6\u80de\u6b7b\u4ea1\u76f8\u5173\u7684\u75be\u75c5\u5f00\u53d1\u5c0f\u5206\u2f26\u836f\u7269 \uff0c\u5305\u62ec\u7ec6\u80de\u574f\u6b7b\u6291\u5236\u5242\u548c\u7ec6\u80de\u51cb\u4ea1\u6291\u5236\u5242\u7b49\u3002\u4e3a\u6cbb\u7597\u8001\u5e74\u75f4\u5446\u75c7, \u5e15\u2fa6\u68ee\u3001\u591a\u53d1\u6027\u786c\u5316\u75c7\u7b49\u591a\u79cd\u795e\u7ecf\u9000\u2f8f\u6027\u75be\u75c5\u548c\u795e\u7ecf\u6027\u635f\u4f24\u7684\u75be\u75c5\u505a\u51fa\u8d21\u732e\u3002<\/p>\n

\"\"<\/p>\n

 <\/p>\n

\u9879\u76ee\u8def\u6f14<\/strong><\/span><\/h4>\n

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\u53cc\u98de\u4eba\u5236\u836f\u603b\u7ecf\u7406 \u66f9\u6b63\u6d2a<\/span><\/p>\n

\"\"<\/p>\n

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\u8be5\u9879\u76ee\u76ee\u524d\u5df2\u7533\u8bf7\u56fd\u9645\u4e13\u5229\u4fdd\u62a4\uff0c\u6709\u4e0d\u9519\u7684\u56fd\u9645\u5e02\u573a\u524d\u666f\u3002\u878d\u8d44\u540e\u5c06\u7528\u4e8e\u5b8c\u5584\u4e34\u5e8a\u524d\u7814\u7a76\u6570\u636e\u3001\u7533\u62a5\u65b0\u836f\u4e34\u5e8a\u6279\u4ef6\u3001\u5f00\u5c55\u65b0\u836f\u4e34\u5e8a\u7814\u7a76\u3001\u7533\u62a5\u65b0\u836f\u8bc1\u4e66\u53ca\u65b0\u836f\u751f\u4ea7\u6ce8\u518c\u6279\u6587\u7b49\u3002<\/p>\n

\"\"<\/p>\n

 <\/p>\n

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\"\"<\/p>\n

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\u4f9d\u636e\u8be5\u539f\u7406\uff0c\u56e2\u961f\u5f00\u53d1\u4e86\u4e16\u754c\u9996\u4e2a\u6eb6\u7624\u75c5\u6bd2\u65b0\u836f\u5b89\u67ef\u745e\uff08H101\uff09\uff0c\u5e76\u5728\u6b64\u57fa\u7840\u4e0a\u5f00\u53d1\u4e86\u5176\u5347\u7ea7\u7248A02\u75c5\u6bd2\u3002A02\u75c5\u6bd2\u611f\u67d3\u80bf\u7624\u7ec6\u80de\u540e\uff0c\u901a\u8fc7\u8ba9\u80bf\u7624\u7ec6\u80de\u65e0\u6cd5\u6b63\u5e38\u8868\u8fbePDL1\u86cb\u767d\uff0c\u4f7f\u5176\u6291\u5236\u901a\u8def\u5931\u6d3b\uff0c\u4ece\u800cT\u7ec6\u80de\u53ef\u6b63\u5e38\u6740\u4f24\u80bf\u7624\u7ec6\u80de\uff0c\u5f62\u6210\u5b8c\u6574\u4f53\u5185\u4e2a\u4f53\u5316\u80bf\u7624\u75ab\u82d7\u3002<\/p>\n

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\"\"<\/p>\n

 <\/p>\n

\u300a\u795e\u7ecf\u7cfb\u7edf\u65b0\u836f\u5f00\u53d1\u300b<\/strong><\/span><\/p>\n

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\u8054\u5408\u521b\u59cb\u4eba\/\u603b\u7ecf\u7406 \u8c2d\u9707\u535a\u58eb<\/span><\/p>\n

\"\" \"\"<\/p>\n

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1\u3001\u9547\u75db\u836f\u7814\u53d1\u7ba1\u7ebf\uff1a\u73b0\u6709\u9ebb\u9189\u6027\u9547\u75db\u836f\u5b58\u5728A\u7247\u7c7b\u836f\u7269\u8fc7\u91cf\u5bfc\u81f4\u6b7b\u4ea1\u7684\u72b6\u51b5\uff0c\u5c24\u5176\u5728\u5965\u5730\u5229\u3001\u52a0\u62ff\u5927\u3001\u4e39\u9ea6\u3001\u7f8e\u56fd\u7b49\u9ad8\u6536\u5165\u56fd\u5bb6\u8f83\u4e3a\u4e25\u91cd\uff0c\u745e\u5065\u5f00\u53d1\u7684\u836f\u7269\u5177\u6709\u9547\u75db\u5f3a\u5ea6\u9ad8\u3001\u65e0\u6210\u763e\u6027\u3001\u4f53\u5185\u4ee3\u8c22\u5feb\u3001\u5242\u578b\u591a\u6837\u5316\u7b49\u7279\u70b9\u3002<\/p>\n

2\u3001\u6297\u6291\u90c1\u836f\u7814\u53d1\u7ba1\u7ebf\uff1a\u6297\u6291\u90c1\u836f\u533b\u9662\u5e02\u573a\u8fd1\u5e74\u6765\u589e\u901f\u5747\u8d85\u8fc7\u4e24\u4f4d\u6570\uff0c\u8fdb\u53e3\u836f\u548c\u5408\u8d44\u836f\u5360\u6bd4\u7ea6\u4e5d\u6210\uff0c\u4e14\u7ea6\u4e09\u6210\u4ee5\u4e0a\u60a3\u8005\u5bf9\u836f\u7269\u8868\u73b0\u51fa\u8010\u53d7\u6027\u3002\u745e\u5065\u7814\u53d1\u7684\u6cbb\u7597\u62b5\u6297\u6027\u6291\u90c1\u65b0\u836f\u662f\u5341\u5206\u5c11\u6709\u7684\u5feb\u901f\u8d77\u6548\u836f\u7269\uff0c\u4e14\u65e0\u6210\u763e\u6027\u548c\u81f4\u5e7b\u6027\u3002<\/p>\n

\u878d\u8d44\u540e\uff0c\u516c\u53f8\u5c06\u5927\u529b\u63a8\u8fdb\u65e2\u5b9a\u7684\u65b0\u836f\u7814\u53d1\u8ba1\u5212\uff0c\u5e76\u5728\u4e09\u5e74\u5185\u5728\u4e2d\u7f8e\u4e24\u56fd\u7533\u62a5\u3002<\/p>\n

\"\"<\/p>\n

 <\/p>\n

\u300a\u57fa\u4e8eMicroED\u7684\u836f\u7269\u7814\u53d1\u5e73\u53f0\u300b<\/strong><\/span><\/p>\n

\u9752\u4e91\u745e\u6676\u521b\u59cb\u4eba\/CEO \u5218\u78ca\u5cf0\u535a\u58eb<\/span><\/p>\n

\"\"<\/p>\n

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