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- \u5e72\u7ec6\u80de\u6709\u671b\u6539\u5584\u542c\u529b\u635f\u5931<\/strong><\/li>\n<\/ul>\n
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\u6e90\u81ea\u4eba\u7c7b\u5e72\u7ec6\u80de\u7684\u542c\u89c9\u795e\u7ecf\u5143\uff08\u9ec4\u8272\uff09\uff0c\u91cd\u65b0\u586b\u5145\u804b\u6c99\u9f20\u7684\u8033\u8717<\/p><\/div>\n
\u00a0 \u00a0 \u00a002 \u8110\u5e26\u8840\u6cbb\u7597\u513f\u7ae5\u83b7\u5f97\u6027\u611f\u97f3\u795e\u7ecf\u6027\u8033\u804b<\/strong>
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\n\u8be5\u7814\u7a76\u572811\u4f8b6\u4e2a\u6708\u81f36\u5c81\u83b7\u5f97\u6027SNHL\u513f\u7ae5\u60a3\u8005\u4e2d\u5f00\u5c55\uff0c\u8bc4\u4f30\u4e86\u9759\u8109\u8f93\u6ce8\u81ea\u4f53\u8110\u5e26\u8840\u7684\u5b89\u5168\u6027\u548c\u521d\u6b65\u7597\u6548\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u8f93\u6ce8\u81ea\u4f53\u8110\u5e26\u8840\u5b89\u5168\u3001\u53ef\u884c\u4e14\u8010\u53d7\u6027\u826f\u597d\uff0c45%\u7684\u60a3\u8005\u5728\u8f93\u6ce8\u540e\u542c\u89c9\u8111\u5e72\u53cd\u5e94\u8868\u73b0\u51fa\u663e\u8457\u6539\u5584\uff08p\uff1c0.05\uff09\u3002
\n\u00a0 \u00a0 03 iPSC\u53ef\u6062\u590d\u542c\u529b<\/strong>
\niPSC\u662f\u4e00\u7c7b\u7279\u6b8a\u7684\u7ec6\u80de\uff0c\u5b83\u6765\u6e90\u4e8e\u4f53\u7ec6\u80de\uff0c\u901a\u8fc7\u57fa\u56e0\u91cd\u7ec4\u6fc0\u6d3b\u5e72\u6027\u76f8\u5173\u901a\u8def\uff0c\u83b7\u5f97\u81ea\u6211\u66f4\u65b0\u548c\u591a\u5411\u5206\u5316\u80fd\u529b\u3002\u591a\u9879\u7814\u7a76\u8868\u660e\uff0c\u6bdb\u7ec6\u80de\u3001\u652f\u6301\u7ec6\u80de\u53ca\u542c\u795e\u7ecf\u5747\u53ef\u901a\u8fc7iPSC\u8bf1\u5bfc\u5206\u5316\u3002
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\u4ebaiPSC\u884d\u751f\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/p><\/div>\n
- \n
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\u513f\u7ae5\u8033\u804b\u57fa\u56e0\u7b5b\u67e5\u5305\u542b19\u4e2a\u57fa\u56e0\u4f4d\u70b9\u548c4\u9879\u57fa\u56e0\u68c0\u6d4b\uff1a\u5148\u5929\u6027\u8033\u804b\u3001\u540e\u5929\u6027\u8033\u804b\u3001\u8fdf\u53d1\u6027\u8033\u804b\u548c\u836f\u7269\u81f4\u654f\u6027\u8033\u804b\u3002
\n\u5176\u4f18\u52bf\u5728\u4e8e\uff1a
\n\u2460\u6307\u5bfc\u79d1\u5b66\u5a5a\u80b2\uff0c\u4ece\u6e90\u5934\u4e0a\u9884\u9632\u8033\u804b\u51fa\u751f\u7f3a\u9677\u7684\u53d1\u751f\uff1b
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- \u603b\u7ed3<\/strong><\/li>\n<\/ul>\n
\u968f\u7740\u5e72\u7ec6\u80de\u6cbb\u7597\u7814\u7a76\u7684\u8fdb\u4e00\u6b65\u5f00\u5c55\uff0c\u4ee5\u53ca\u57fa\u56e0\u68c0\u6d4b\u7684\u8fdb\u4e00\u6b65\u666e\u53ca\uff0c\u76f8\u4fe1\u672a\u6765\u4f1a\u6709\u66f4\u591a\u542c\u529b\u969c\u788d\u60a3\u8005\u91cd\u83b7\u542c\u529b\uff0c\u60a3\u8005\u6570\u91cf\u5c06\u8d8a\u6765\u8d8a\u5c11\u3002<\/p>\n
\u3010\u53c2\u8003\u6587\u732e\u3011
\n[1] Chen W, Jongkamonwiwat N, Abbas L, et al. Restoration of auditory evoked responses by human ES-cell-derived otic progenitors[J]. Nature, 2012, 490(7419): 278-282.
\n[2] Baumgartner L S , Moore E , Shook D , et al. Safety of Autologous Umbilical Cord Blood Therapy for Acquired Sensorineural Hearing Loss in Children[J]. Journal of Audiology & Otology, 2018, 22(4).
\n[3] Kazuo, Oshima, and, et al. Mechanosensitive Hair Cell-like Cells from Embryonic and Induced Pluripotent Stem Cells[J]. Cell, 2010, 141(4):704-716.
\n[4] Tang Z H , Chen J R , Zheng J , et al. Genetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells[J]. Stem Cells Translational Medicine, 2016, 5(5):561.
\n[5] Lee H S , Woo J , Kim, et al. clinical safety and efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in sensorineural hearing loss patients address for correspondence[J]. 2018.<\/p>\n","protected":false},"excerpt":{"rendered":"\u8fd1\u5e74\u6765\uff0c\u591a\u9879\u79d1\u5b66\u7814\u7a76\u8868\u660e\uff0c\u5e72\u7ec6\u80de\u6216\u80fd\u7ed9\u8033\u804b\u60a3\u8005\u7684\u6cbb\u7597\u63d0\u4f9b\u65b0\u9009\u62e9\u3002<\/p>\n","protected":false},"author":2,"featured_media":8679,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[116],"tags":[67,143,150],"acf":[],"yoast_head":"\n
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